The only real difference is that Rage leaves a big-ass entry hole, where the Hypershock doesn't.

Once inside, the Hypershock will do more damage (and have more killing power) by virtue of the bigger cutting diameter. If it doesn't exit, it just won't leave a gigantic exit wound.

Either way, I don't think it'll matter a lick, b/c you could probably shoot a deer square in the guts with a head that big, and it wouldn't go 100 yards before it would be too sick to go any further. In all honesty, that's the true fudge-factor that a lot of guys are looking for.