I'm partial to Hornady's and have used the Interlocks on everything from grizzly,moose ,elk,blackbear,caribou,deer to antelope with no bullet failures.Your .257 would work nice for deer with any of available weights starting at 100gr,117gr and the 120HP.The 117-120 will tilt a elk or moose if you do your part.Personally I think the ballistic tips come apart if pushed beyond 2800 fps.When deer are shot from100 yards out and farther with this bullet it seems to work as intended.Jumping deer out of beds at pointblank is another matter entirely.Grenades.......BTW your .257 is a very well balanced sensible cartridge...........Jack O'Conner spoke highly of his.............Good shooting....Harold