At the risk of offending the folks who like to blow a deer in half to be sure it dead, I have to say that I used to use the hot core speer bullets. They however damage a lot of meat. I second the Hornady Bullet although the Barnes X bullet would be my choice for a 25-06 and 243 Win. 100 gr. X for the 25-06 and either the 85 or 90 grain X in the 243.