Hey fellas, I'm debating building myself a medium weight, sporter rifle for a multi-purpose North America big game rifle.

Cartridge:

I'm kinda thinking a 280 Ackley Improved.

Whatcha guys think of that for shooting antelope, mule deer, whitetails, elk, and sheep.

What other cartridge should I check into?

I will more than likely build it on a Savage action, Shilen barrel, and a Stockade gun stock.