Hey Johnny2, I checked my Mustang records and can give you some poop on my experience with Lee 250 grain REALs. I shot some last May over a chronograph, usingPyrodex RS and a 1/8" Circle Fly fiber wad under the bullets.

(All groups were five shotsat 50 yards.)

70 grains powder - 1281 fps average - four shots into 1 & 7/8"- one flyer expanded group to 3 & 7/8"
80 grains powder - 1375 fps average - four shots into 1 & 1/2" - one flyer expanded group to 2 & 7/8"
90 grains powder - 1420 fps average - four shots into 1 & 3/8" - one flyer expanded group to 3 & 1/8"
100 grains powder - 1510 fps average - four shots into 2 & 1/4" - one flyer expanded group to 2 & 7/8"
110 grains powder - 1581 fps average - five shots into 2 & 3/4"

DANG those flyers! Sometimes it was the first shot, sometimes the second, third, fourth, or fifth. (It couldn't possibly have been my shooting! ) Good shooting records are nice to have.