My first "good buck" came at the hands ofa 2506 rem and 115gr partition, anchored him to the snow with a punch right on through both shoulders and the bullet exited. By good I mean a mature saskatchewan buck with a 150 class rack and 300# frame. I thinkthe gunsmith you mention must have gotten his infoto my hunting buddiesat time as well, they somehow talked me out of using the 2506 for deer

. Since thenI have actually learnedthe 2506 rem is a perfectly suited deer cartridge, having seen numerous deer shot with it and other 1/4 bores. Couple it with Nosler part, Barnes TSX or similar and you can take all the raking shots you desire on deer sized game. If longer range is your usage model the 110 ABmay be thecandy you choose. Good bullet selection for the reloader as well. What can I say i like it!
270win vs. 2506rem both capable. I own both currently and ifthe 2506rem was in a LH action I'd pick it over the 270win actually. I see absolutely nothing wrong with a 115gr nosler partition at 30-31K.