The 250SW will likely not load with the sabots supplied...at least not in either of my Omegas. You'd have to get slightly smaller sabots.

As for performance on game, I have not used the 250SW but have taken probably 30+ deer with the 200gr SW. I have never had any performance issue, 110gr 777. I have a bullet that took down a deer at 209 yards this year, fully expanded back to the base. At that range the velocity was well below the 1900fps mark! I also had a complete pass-thru and bang-flop at 338 yds.

If anything, the SW can over-expand and separate from the jacket at close-range, bone-hitting shots. However in my experience this has always been on the far side of the deer after all necessary damage was done (jackets recovered under far-side skin and lead exited). Has happened maybe 3 times in 15-18 such shots.

I wonder is people complaining about not expanding are shooting the bonded version, which isn't really needed for deer...