RE: 85 grain, 100 grain, 125 grain
Choose a spine that will handle a 125 head and enjoy the extra FOC. The speed difference in a 125 grain to 85 grain head would be only 10fps or so. Hardly earth shattering. You can still arrive at a lighter arrow by choosing your shafts accordingly. I do shoot some of my arrows with 100 grain heads, but generally those have weighted inserts.
Dan