I have shot alot of mule deer with a 243win. 100gr. Core-Lokt bullet. This last season used a 150gr. Winchester Power Point out of a 270wsm. Took a mule deer doe at a lasered 298yds. Here is the results.
http://i248.photobucket.com/albums/gg178/700xcr/1209070959-00-01.jpg
http://i248.photobucket.com/albums/gg178/700xcr/1209071041-00.jpg