I have a friend who uses a 450 Marlin for deer..lol...he loves it. Overkill ?? Heck yes...but this is America and its his choice.
I have one to that I bought for hog hunting it is bigger than I needed but I like it. I also usedit on deer and it will put a big hole through them but it doesn't blow out the far side like a lot of the higher velocity rounds do. Like someone said about the .45/70 one time you eat right up to the hole.