RE: 50 cal knockdown power
Sounds like you either a) missed the vitals or b) the bullet hit bone and fragmented explosively on the surface.
I've shot all types of bullets and killed over 100 deer and never had one hit through the lungs or heart go far. The few bad shots sometimes resembled what you described.
Without being too graphic, I've helped track deer than lost half their digestive tract to one or more 12gauge slugs and made it half a mile or more. Devastation doesn't mean much if it isn't the chest, and if you're in the chest the difference between bullets isn't very significant.
I've tried the 300gr Precision Rifle Keith Nose hollowpoint, a hunk of soft lead with a gaping wide hollowpoint. They expand more than the size of a quarter, yet don't put deer down any quicker than a 200gr Shockwave.