I use the same powder - RL-22 at 67.5 grains -with Winchester WLRM primers. I have an A-bolt eclipse with the BOSS and my chamber is a little long (distance to lands with the accubond is 3.352") and I set the oal at 3.336 to 3.338" Accuracy is very impressive - not uncommon to shoot 5-shot, 1/2" groups at 100yds (with the BOSS set at 2.6). This comes out at 3050fps. I have moved up to 68.5 grains with no pressure issues and just modest velocity increases - 50 to 75 fps, but accuracy is about the same.

Fishhead has it right - great holes in deer. If you're used to a small entry and big exit, get ready for big entry and big exit. The deer seem to drop a little quicker with the Accubond than with the TSX bullets, in my experience.