Tom, I would start with IMR3031. Its a classically 45-70 powder good for bullets from 300gr to 500gr. But thats me. And if its a deer hunting gun, I would start with 300gr sierra or 350 Hornady. Its a reg primer.
Lyman makes a nice die Head is talking about. I would suggest this myself. The M die does a great job at nice straight seating. See pict below
http://www.midwayusa.com/eproductpage.exe/showproduct?saleitemid=507130&t=11082005