In my mind the biggest problem with long shots from a muzzleloader (200+)is not the ability of the bullet to kill but the potential for the target to move. Between the concentration required to make shots at long range, the delay in trigger pull, the relatively slow speed of a MZ bullet it is easy for too much timeto elapse between the brain's decision to fire and the bullet's arrival on target. One step forward by the animal, even a weight shift, and a deer sized animalcan move 6-12 inches. To me, that is the ethical dilemna.