I'd be hesitant to blame your ammunition, since there are more than a couple variables at work once a bullet strikes an animal.

I've used "cheapo" CoreLokts and PowerPoints, not to mention Hi-Shoks, for years in .30-06 and .243 and haven't had any issues finding game I've hit, minus one poor shot that was MY fault. It's hard sometimes, but it's been helpful to me to settle down a bit after the shot myself, noting where the deer was when I fired, and which general direction it left in. I'll generally mark the site of the shot with orange engineer tape, whether I find any signs of blood or not. From there, I'll look for tracks (generally kicked up leaves, other signs that a deer left in a hurry) as well as blood, going in the direction I saw the deer leave.

The worst effects I've experienced, though still resulting in a downed animal, were with handloaded Sierra GameKing BTs. They ALWAYS shed their jackets, scattering bullet fragments all over in a deer or antelope. I've since switched to "cheapo" Hornadys and haven't had any problems, but still wouldn't cancel a hunt if all I had on hand were CoreLokts, PowerPoints, or Hi-Shoks.