I'm a big RB fan, but I've never liked the idea of using them beyond about 75 yards. They just don't keep their speed and energy up very well at longer distances. With either of the loads you're talking about, I wouldn't have a worry in the world with deer because I consider them more like elk or moose loads. On deer, I'd probably try my best to get an angle to take out the lungs and a shoulder, just to givethe ballsome work to do and put the deer down right there.