Ditto the no mechanicals. As for shot placement, there may be some who would argue the point but my favorite option would be a quartering away shot. Just physically aim for the opposite shoulder and I think I would hold my pin 1.3 of the way up from the belly just as you would a deer.

This shot should get you in behind the extra thick hide that protects the vital zone.

I took a 350 lb Russian Blue in the Tarsus Eucalyptus Forest many years ago; but I got mine with a 12 ga pumpkin ball down his nose. I' m not sure how well an arrow would penetrate in a standard broadside shot . . . but it should work.