180 gr. factory loads its almost a coin toss (WSM slightly better). I would choose the WSM cause its newer technology, and you can get a lighter factory rifle. Plus I noticed this year that Cabelas sold out of WSM, but had pleanty of 300 Win. This means: 1- a shift to WSM which will make factory loads more available down the road, 2- less WSM so they sold out. I tend to lean towards the first. However, you can hand load a 300W much hotter/heavier. I agree with cma though, if a 180 TSX wont take it down, you best run.