I'm shooting 115gr Combined Technology BTs out of my 25WSSM, and I have shot 2 large deer with it so far. The first one was a doe at a lasered 429 yards, she ran close to 100 yards after being shot (thru the boiler room), just a puddle of gelled lungs. The second was a buck at 175 yards, and his lungs/heart were also a pile of gel, and he still ran a good 60 yards. This is the first centerfire round I have shot a deer that has moved more than a few feet. Still not sure if I am impressed with it or not.