Mostof the time I aim just behind the leg for the bottom of the lungs, this gives me room for error both up/down and side to side. I honestly haven't had a deer travel much further then 100 yards with a double lung shot, which i think is a pretty quick drop. All said my favorite shot is a 1/4 away where I hit the vitals realitively unobstructed and take out the opposite shoulder on exit, here I aim for the top portion of the lungs so I ensure I hit scapula on the exit and not leg bone.A double shoulder shot is highly effective if you get enough pentration for both shoulders or at least lots of damage on the onside shoulder to effect both upper lobes of the lung. Deer can go a long way with one wheel and lung. My experience with polymer tipped bullets hitting heavier bone, especially at higher MV's (ie close range or hotter loads), makes me suspect relability and thus I'd either move up gr size or chose a more robust bullet like barnes, nosler, etc.