Your .243 Win, .243 WSSM, or 7mm-08 TC Pro Hunter are probably your best choices. Take whichever you prefer of those three (probably the one that has the best optics). A 300 and 338 will do the job, but they're definately overkill. Even my 7mm Rem Mag is a little overkill, so I started using my .243 that I bought for varmint hunting this summer. It piled up a nice buck at 75 yards, and my brother put another buck down at 200 yards. Both nice, clean kills without the gaping hole my 7mm Rem Mag used to leave.