Any bullet you choose for a 300 mag will "over penetrate" a deer. Although i prefer to have a bullet "over penetrate" and give me two holes to drip blood instead of just one
By over penetrate I mean that the bullet is built toooo tough for expansion in the body cavity of a bullet...anyone I know that uses a 130 grain failsafe in a 270 win has never found the bullet that went thru an Elk they had shot.
I have heard nothing but bad things about Accubonds and their work on game..I have never used them using just partitions and or failsafes with complete satisfaction. I don't think a cold bonded bullet is the same as the original heat bonded bullet such as an Aframe. Personally I think the Barnes MRX ( an xp3 copy) and the xp3 are the finest big game bullets made today.
. Ballistically there isn't a hill of beans of difference between a 150, 165 or 180 grain high BC bullet. At 400 yards you are only talking about 3-4" advantage with the lighter weight bullets.
Shoots flatter and kicks less and does a ton of damage what is not to like? In fact in my 300 wsm with a 1/11" twist the 150's shoot like no tomorrow and I haven't bothered shooting anything heavier even though I have the bullets at home.