Had a buddy that used a 45-70 to shoot coyotes from his garage window. Vernier tang sight, range 365 yards, very good accuracy, but............ with the rainbow trajectory it was only good for that exact range (he had a deer carcass pile there).
I used to have a 45-70 pistol barrel for a contender I owned. I scoped it and at 100 yards could hit a pop can every shot if I did my part. Back then they weren't legal for deer hunting, so I finally traded it off. Nor they're legal........... what's the old saying about hindsight being 20/20.........[:@]And with a 350 grain bullet and 45 to 50 grains IMR4198 you didn't have to look at the primer to see if the firing pin hit.