I shoot one and will be trying it on deer next year. I know that with a little practice and the right load worked up it is plenty accurate out to 100 yards and packs a heckuva wallup out to that distance. I think that 357/38 is a bit light for deer past about 50 yards, but with the right shot a guy might get away with taking a deer out to 100 yards with one. There is also the 45LC, it should be able to do everything that the 44 Magnum does but with just a bit more bullet drop. If a guy handloads you can get pretty close to the same performance as with a 44 Magnum. Both are just a blast to shoot and very easy to handload for.