I like other posters here have taken many deer with the 30 caliber rounds (-06 and 308 Win.) My favorite is the Nosler ballistic tips in 168 Gr. I also have used the 150's with great success. I have loaded all sorts of partitions, accubonds, Speers, Sierras, Hornady's etc., and have (with my friends help) droppedclose to 40 deer with these rounds. They all work....exceedingly well. Shot placement as others have said is a much more critical element in the equation. 168 BT's seem to do it just a little better than most.......