RE: .280 Remington
CorBon & Federal both load the 140 gr. Barnes TSX bullet for the 280. I handload this same bullet to an average velocity of 3043 fps with 1/2 MOA accuracy out of my custom Remington 700 w/25" barrel. I allowed my best friend to use the rifle last year on a Colorado elk hunt. He took a 5X6 bull at 302 yards with this load. The bullet entered the shoulder plowed through to the other side and exited. He said the bull staggered about 10 feet and dropped.
I personally have removed many feral hogs from my property with this same load. Last deer season I shot a huge sow in the rear end at a little over 100 yards. The bullet traversed the body and exited out the front end. I estimate the sow weighed 280-300 lbs. I don't use this bullet when deer hunting, but I keep a few in my pocket in case I see some hogs. My deer bullet is the Hornady 139 gr. & it and the TSX have nearly the same impact.