1 st... Yes, sight in with whatever ammo you will hunt with. Rem. ballistic tip ammo is fine.

If you have a area where you can sight in at 100 yards, then use it. Shoot at 25 yards to make sure it is bore sighted to paper.... If it is , then go back to 100 yards and sight dead on to 1 " high at 100. If you have a 150 yards max, that set up will do everything you need it to do sighted this way.

If the gun is not printing good on paper at 25 yards, then use a couple of shots to get it there, and then move back to 100. It doesn't have to be perfect at 25 yards, it just has to be close enough that when you shoot it at 100 yards, You will be able to see the target impact and make the necessary scope elevation and windage adjustments to get it where you need it.

And the reason sighting at 100 yards is better, is because it will allow that distance to open up the shots showing your personal shooting ticks , pulls, and flinches, and sight in your gun allowing for them. If you shoot it only at 25 yards , then you shoot at a deer 150 yards out, I can promise you there will be a difference. At 25 yards you can almost shoot the gun with open sights and do as well. The distance is not great enough to allow much error. The greater the distance , the more your shooting form errors shows up.

Good luck