I think what you are saying is.. can temperature effect the way a bullet shoots? Well the answer is yes, there does seem to be an indication that drastic changes of temperature can effect bullet flight. I sometimes wonder though, are we changing the way we do things. We wear different thickness clothing, we react to the cold body wise in differnt ways, etc.

Take the rifle, find a load and stick with it. Normally once you get that tuned in, even cold weather should not effect too much. Once you have a meat and potatoes load, then you can play and tryall the other stuff.