Personally I can' t think of a good enough reason to take the .270. I mean I' m from ohio and the biggest thing I' ve been hunting for is whitetail/wild boar, but if I' m going into grizzly area I would take the bigger gun it' s not like the 350 isn' t gonna kill the caribou and the .270 would but the 350 might work on the bear and the 270 might not. Anyways good luck on our hunt, wish I was going.