Ive shot a bunch of deer with the 200 gr nosler in my 338. Its the most accurate bullet Ive found for that particular rifle, and usually most any rifle Ive tried nosler bt' s in will shoot them very well. I actually prefer a bullet that is a little tougher though for game, and only use these because they have enough weight to punch through a whitetail even though they usually turn inside out even on a small deer. I guess the deer dont care though. I have seen some dismal performance on deer with the lighter calibers though and personally wont use them in my 7mm rifles because of what Ive seen.