The Remington Shoot program says to be 4.5 inches high at 100 yards so that you hit the bull at 300 yards. I never liked doing that since it makes it hard to hit anything under 100 yards if you zero like that. 2-3 inches high at 100 should allow you to hit anything out to 300 yards. Just make sure that you get it grouping consistantly at 100 yards and you should be doing allright. Most game is taken under 100 yards and closer to 50 anyways.