How about medium wieght and medium velocity? I know its not very " fashionable" but it is exactly what worked for many years. Before that it was slow and heavy. The rage today seems to be light and fast. Dead is dead.
The fact is that it is a combination of more than 2 factors. It is bullet wieght combined with bullet construction with an appropriate velocity for the job at hand. Fact is for most all north american biggame hunting velocities from 2400 fps to 2900 fps in bullet wieghts of 130 - 180 will suffice nicely when the hunter does his job.
Shoot whatever you like and whatever does the job for you.