Switch to 110 2f T7, 300 gr Nosler Partition, Win 209 Primerand you'll get the holes you want! This load shoots nicely in my Omega and is accurate out to 200 yds and still maintains over 1000 ft lbs energy at that range. Zero at 153 yds for a 6 inch kill zone and you're good to200 yds.
I shot this load over a chronograph at the muzzle and 100yds, so I know those numbers to be accurate and I suppose the math takes over from there cause I don't trust myself to shoot over the chrony at 200. lol

Load Data
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Name: .451 Cal, Nosler Partition PP, 300 grn
Ballistic Coeff: 0.199
Bullet Weight: 300
Velocity: 1914
Target Distance: 250
Scope Height: 1.500
Temperature: 70
Altitude: 500
Ballistic Data
~~~~~~~~~~~~~~~
Range Elevation Velocity Energy ETA Drop Max Y 10mph Wind Deflect
0 yds -1.50 in 1914 fps 2440 fpe 0.000 sec 0.00 in -1.50 in 0.00 in
25 yds 0.67 in 1825 fps 2219 fpe 0.040 sec 0.31 in -0.52 in 0.17 in
50 yds 2.18 in 1740 fps 2017 fpe 0.083 sec 1.28 in -0.27 in 0.74 in
75 yds 2.95 in 1658 fps 1831 fpe 0.127 sec 2.97 in 0.19 in 1.68 in
100 yds 2.95 in 1579 fps 1660 fpe 0.174 sec 5.45 in 0.86 in 2.95 in
125 yds 2.12 in 1502 fps 1502 fpe 0.222 sec 8.75 in 1.79 in 4.52 in
150 yds 0.29 in 1430 fps 1362 fpe 0.273 sec 13.06 in 3.02 in 6.63 in
175 yds -2.63 in 1363 fps 1237 fpe 0.327 sec 18.46 in 4.59 in 9.24 in
200 yds -6.73 in 1301 fps 1127 fpe 0.383 sec 25.03 in 6.54 in 12.28 in
225 yds -12.06 in 1243 fps 1028 fpe 0.442 sec 32.84 in 8.90 in 15.74 in
250 yds -18.84 in 1191 fps 944 fpe 0.504 sec 42.10 in 11.74 in 19.71 in
275 yds -27.16 in 1144 fps 872 fpe 0.568 sec 52.89 in 15.08 in 24.12 in
300 yds -37.14 in 1104 fps 812 fpe 0.635 sec 65.35 in 18.99 in 28.97 in