.458 Lott and .458WM are both from the same parent case, the .375H&H. The Lott is just a full length case the win mag is shortened. You can fire the win mag in the Lott chamber, you can also load the win mag down to 45/70 ballistics and use cast bullets. The 45/70 won't chamber in the win mag or Lott because it is rimmed the other two are belted. But you still have the versatility of using several rounds in the same gun. If you want to get really exotic, the Ruger #1 is also available in .416 Rigby or 470NE : )