In my CVA Staghorn that I shoot 90 grains of Pyrodex RS and a 245 grain Powerbelt. It is sighted in dead on at 100 yards. The 75 yard station will normally put that powerbelt on the very top of the bullseye I am shooting. At 50 yards, about two inches above dead center of the bulls eye. At 25 yards about an inch above dead center. On a deer kill zone.. if your sighted in dead center at 100 yards, just aim dead center in the kill zone of the deer and let the bullet take care of the rest of your problems. Although it would not hurt to take a trip to the range and double check it all.