I shot my first few deer with a 7mm remington mag with 150gr bullets. It worked like a sledge hammer, never lost a deer, never had a deer take a step. I then got a Browning 243 at a good price and decided to use it. Shot a nice deer at 280 yards, both shoulders, watched it drop in its tracks. It was nice to be able to see the bullet hit through the scope, never could do that with the 7mm. Well that about did it for my 7mm, after that I used the 243 for all my deer hunting, even sold the 7mm. I use fed prem 100gr SBT and have killed 11 deer with 11 shots, never lost a deer never had one go more than 25 yards and watched the impact on all of them.