I've hunted deer the past 35 years using 150 and 165 grain Hornadys and 4064. Look the loads up in the manuel, your gun may not shot the same as mine. Only killed two deer with any other load. First one was with a .44-40 with factory loads and the other with a .30-40 Krag using 180 grain factorys. The 180's were the only ones to exit. All the deer droped in ther tracks except one which went about fifty yards. These were all Columbia Blacktails.