When i get a new rifle i buy at least 3 different bullets to start looking for the one it likes. Usually have 5 or 6 different powders on hand so I start working with what I have.
I play with seating depth as much as possible except that I've found 3 of my rifles don't allow seating just off the lands as the bullets catch up in the clip. So I have to seat them deeper in the case. Seated out is good on the range as a single shot but no good for hunting.
I love to load and shoot and everytime they come out with a new bullet I gotta try it. Hornady and Nosler in March.
Now to answer your question, I don't look for the quickest way. Trying 3 or 4 different bullets and 5 or 6 different powders is what I look forward too when I get a new rifle.