I think the guy who said most shooters are not qualified to shoot moa consistently is correct. Also, I'm guessing I'm not in the qualified group. I find it hard to consistently shoot a group of 5 that I'm satisfied I didn't pull just a little bit.

I have found, limited though my shooting ability may be, that my rifles shoot differently with different factory loads. My .25-06 shoots reasonably well with Hornady Custom ammo but poorly with several other kinds of ammo. I can keep my groups under about 1.5" with the Hornady but find that I can't do better than 2.5" or even 3.5" with some other ammo. As I understand it, this is not an indication of the poor quality or variability of this other ammo, but just an instance of a rifle having a particular resonant frequency which agrees with some ammo and not with others. In another .25-06 rifle the Hornady Custom ammo may perform poorly and one of the loads that performs poorly in my rifle may be perfect in another rifle. So go try about 5 different commercial loads in your rifle.

Of course, if you hand load you can use fire-formed brass and tune your load to your rifle. I don't reload, but I've been attracted to this aspect of reloading -- tuning loads to shoot very well in each of my rifles.