In a basic sense I tend to agree with Paul. When you choose a particular setup it should be done taking into account ALL situations that you may incur. In your case that means being able to draw the bow smoothly in every situation. It's no secret that cold temperature mean cold and stiff muscles, making that first shot harder to draw than if you were warm or warmed up.

If it's just a special situation then maybe drop the bow weight for that hunt. Maybe have different arrows for that setup. And maybe buy a sight and sight it in just for that hunt. Or, if you have the money, a complete different setup just for that cold stuff.

Easier drawing cam bow or maybe drop the weight to about 55 or both and see what happens.