In my encore I use 100grs., of SHKY Gold, loose with a 250 grain SW. My accuracy has been very good out to 175 yds. Haven,t shot past that distance. If using SG or APP, that powder tends to like a heavier bullet. Going to experiment with 300 grs. a bit later on. You will have good accuracy with the 180's, but careful on your long range shots as the FPKE drops rapidly. 110grs of SG is a good load also. Here in So. Illinois anything over a 100 yd shaot is rare unless you are hunting fields and food plots. The average MLshot is probably closer to 50-70 yds. I hunt with my encore like I do with my bow, (40yds & under) I like them up close and personal, just like to have the option to reach out and touch em if I want. Good Luck!!