paul, what do you consider "medium range" for woodchucks and targets??

if its 350 or less, id probably opt for a 22cal. really, no need for the 243 till you get passed 500...personally, i had the same choice, and i went with the 250. like you said, ammo is comparable when shooting decint/premium ammo. i just liked the little more the 250 has behind it. ive reached out to 350 with my 250 and put 40 chucks down this summer...i think i only had 2 make it to their holes due to bad shots...if my range was definently 350 or less id look at the 223, 222s, 204 etc...just for less recoil. all depends on what you consider medium range...but out to 350 i havent felt undergunned with the 250...the 223 would also work well for me im sure...

when you get into the 500+, thats when youll want the 6mm's/243s etc...more gas and heavier bullets..but i dont see the need for the recoil at shorter ranges....though, it would work nicely. heck...i used my deer rifle, a 3006 out to 300 for chucks for a long time till this year...talk about unneeded recoil