I got away from regular constructed 100gr bullets in the 25-06 due to excessive meat damage and eratic penetration.I use 115gr partitions backed by 54gr of RE22 or 54gr ofH4831SC behind 120gr HornadyHP'S and it settled down.On the other hand in my Rem 700 Classic .250 Sav I load either 100gr Sierra's for deer and 100gr Partitions for anything bigger 41gr Win 760.My old Sav99 has the 1-14 twist so it shoots 87gr bullets best and I end up feeding it 87gr Hornady's/Speer with 32.5gr of IMR 3031 and avoid the shoulder blade altogether.It isn't bad with the short 100gr Speer offering........................Harold [the mulie in the picture met the .250 Rem Classic last fall]