The Hodgon line of powders are all suposed to be non-temp sensitive.I use H-4831 SC in my .338 Win Mag all the time with225gr Hornadys.Re22 in my 6.5x55's [140gr]+RE22 54gr with 115gr Partitions in the 25-06,54gr of H-4831 SC for the Hornady 120HP Same gun.I should chrony the RE22 loads in -20F and see where they are at compared to 0 F.The deer ,moose and elk havn't complained at any velocity loss so far but there's bound to be some with RE22..................Harold