if you bend at the waist and shoot with the same anchor points you should hit the same as you would from the ground.

for most typical bowhunting, i think most guys shoot the range of the target from the base of the tree to the target. within 30yds or so you might be off a yard or 2...i cant remember the real numbers but its nothing to worry about...

definently PRACTICE it though. its a little different and can feel akward. i had to get used to shooting with my feet so close and bending at the waist etc. shooting with my buddies at a 3d shoot today, the last target was a treestand shot. you could tell who didnt bend at their waist...