The 44 mag is a very versatile round, that is within it's limitations, especially from a handgun. I have the same revolver, with the 7.5 inch barrel. It works well on deer at close ranges, longest shot I've ever taken is about 60y, leaning against a tree. As for use on coyotes, I've never tried it. I get the best groups using 240 gr semi jacketed hollow points, my gun especially likes hornady ammo.