Couple years ago me and a buddy went for elk, both armed with .270's. Mine was fed 150 grain Hornady Interlock.
He took a huge bull, put two rounds of 150 grain Nosler Partitions into him and he only went a few yards. The second round was only because a neighboring property would not allow hunters on their land, even if to recover an animal. So the plan in that particular field was to keep shooting 'til it fell down. One pass through, one recovered on the far side... both through the vitals, end of story !!