I've tried magnum (3-pellet) charges in a T/C Omega, but couldn't see any real reason to use such a charge for hunting. At 200 yards it grouped barnes 300 gr Expanders pretty well (3 to 4" groups), but since most of my shots are under 100 yards I couldn't see the point of suffering the recoil that load produced.
Tried 120 grains of loose 3f in my Lyman Mustang today, and it says HELLO when you pull the trigger. [&:]