What discernable difference could there be? That's the question as I see it. I mean, both are going to hit the target YOU aim at. Probably get a little more speed out of the CE's but is iteven measurable (comparing gpi).
Both are available with Blazers.

The big difference as I see it is the shaft diameter. The CE 250's are .289" and the comperable 400's Axis are .265. Not a lot, but enough to maybe sway a guys thinking. The narrower shaft might not match up well with your rest. I know (I use the Axis 400's) that the narrower shaft does not match up well with most broadheads. They are narrower than the broadhead "shoulders" which doesn't really matter 'till you pull them out of a target. So youmight look at your set up and see if the shaft diameter makes a difference.
I like the Axis for the hidden insert, adjustable X knocks, straightness, I shoot 27 1/2" so the shaft is pretty stiff.I use the same arrows for shooting 3-D and target night at the range too.
I'd put the savings in my pocket and spend it on some Slick Tricks!