What I find is a good dynamic bow setup and arrow combo, it won't matter much. But a bow setup where the arrow spine is on the edge, it will. I have seen guys, including Len on here who has like 3-4 different broadheads mfgin thier quiver and they all hit the same POI. (I figure it was cheap samples he gets as a dealer cause Len is cheap.

). just kidding len.
Recently, I have done alot of playing with a bow trying to get it perfect. I shoot bullet holes thru the paper with 100gr or 125gr tip. The 125 of course dives quicker past 25 yards, but both are shooting well. Which I am kinda glad cause I am going to CO in Sept to elk hunt and want to use 125gr BH's.